2,4-DICHLOROQUINOLINE
- Product Name
- 2,4-DICHLOROQUINOLINE
- CAS No.
- 703-61-7
- Chemical Name
- 2,4-DICHLOROQUINOLINE
- Synonyms
- AURORA KA-3862;IFLAB-BB F1706-0118;2,4-DICHLOROQUINOLINE;Quinoline,2,4-dichloro-;2,4-Dichloroquinoline>2,4-Dichloroquinoline 98%;2-4-Dichloro-1-azanaphthalene;2,4-dichloroquinoline(SALTDATA: FREE)
- CBNumber
- CB4757939
- Molecular Formula
- C9H5Cl2N
- Formula Weight
- 198.05
- MOL File
- 703-61-7.mol
2,4-DICHLOROQUINOLINE Property
- Melting point:
- 52-54
- Boiling point:
- 282°C(lit.)
- Density
- 1.4178 (rough estimate)
- refractive index
- 1.6610 (estimate)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- solubility
- Chloroform, Methanol
- form
- Solid
- pka
- -1.10±0.50(Predicted)
- color
- White
- λmax
- 305nm(MeOH)(lit.)
- InChIKey
- QNBJYUUUYZVIJP-UHFFFAOYSA-N
- CAS DataBase Reference
- 703-61-7(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi,T
- Risk Statements
- 36/37/38-41-37/38-25
- Safety Statements
- 26-36-45-39
- RIDADR
- 2811
- WGK Germany
- 3
- Hazard Note
- Irritant
- HazardClass
- 6.1
- PackingGroup
- Ⅲ
- HS Code
- 2933491090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H301Toxic if swalloed
H315Causes skin irritation
H318Causes serious eye damage
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- D4452
- Product name
- 2,4-Dichloroquinoline
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $82
- Updated
- 2024/03/01
- Product number
- D4452
- Product name
- 2,4-Dichloroquinoline
- Purity
- >98.0%(GC)
- Packaging
- 25g
- Price
- $244
- Updated
- 2024/03/01
- Product number
- D436225
- Product name
- 2,4-Dichloroquinoline
- Packaging
- 1g
- Price
- $50
- Updated
- 2021/12/16
- Product number
- FD42902
- Product name
- 2,4-Dichloroquinoline
- Packaging
- 1g
- Price
- $50
- Updated
- 2021/12/16
- Product number
- OR3822
- Product name
- 2,4-Dichloroquinoline
- Purity
- 98%
- Packaging
- 1g
- Price
- $22
- Updated
- 2021/12/16
2,4-DICHLOROQUINOLINE Chemical Properties,Usage,Production
Uses
2,4-Dichloroquinoline is used in the synthesis of tRNA synthetase inhibitors with antibacterial activity against gram-positive bacteria. Also used in the preparation of arylquinolines displaying anthelmintic properties.
Synthesis
The synthesis of 2,4-dichloroquinoline is as follows:A suspension of quinoline-2,4-diol (150 g, 931 mmol) in POCl3 (975 mL, 10.4 mol) was stirred at reflux for 6 hr and the reaction mixture was concentrated. The residue was diluted with CHCl3 (500 mL) and the solution was poured into ice water. The aqueous layer was extracted with CHCl3 (three times). The combined organic layer was dried over MgSO4, filtrated, concentrated, and purified by flash chromatography (silica gel, 20% EtOAc in hexane) to give 2,4-dichloroquinoline (177 g, 96%) as a pale brown solid.
2,4-DICHLOROQUINOLINE Preparation Products And Raw materials
Raw materials
Preparation Products
2,4-DICHLOROQUINOLINE Suppliers
View Lastest Price from 2,4-DICHLOROQUINOLINE manufacturers
- Product
- 2,4-DICHLOROQUINOLINE 703-61-7
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-09-26
- Product
- 2,4-DICHLOROQUINOLINE 703-61-7
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 99%
- Supply Ability
- 1000KGS
- Release date
- 2019-12-20